Mildred Waltrip was an American artist and illustrator.

Waltrip suffered from polio during her lifetime, and wore leg braces. She received her art education at the School of the Art Institute of Chicago.

Waltrip took part in the Works Progress Administration's art program, completing the murals World Map and People and American Characters in 1938 at the Hatch Elementary School in Oak Park, Chicago. In 1995 the murals were removed, as they portrayed Africans stereotypically, "carrying spears, wearing loincloths and sporting prominent red lips". The removed murals were placed in storage.

By the mid 1950s she was illustrating children's books, including Molecules Today and Tomorrow and Research Adventures for Young Scientists.