Luigi Ademollo was an Italian painter.

He was born in Milan. He studied at the Brera Academy, where he was taught by Giulio Traballesi, Giocondo Albertolli, and Giuseppe Piermarini. He left Milan in 1783 and traveled and worked in Rome and Florence. He married Margaret Cimballi Ferrara in Rome in 1792 and had several children. Ademollo primarily painted frescoes with biblical scenes from the Old and New Testaments. In 1789 he was appointed professor at the Academy of Fine Arts in Florence. He painted in theaters, including the decoration of sipari (theater curtains). He helped fresco the Royal Chapel in the Pitti Palace and also the churches of Santissima Annunziata and Sant'Ambrogio. In Siena, he painted frescoes for the Palazzo Venturi Gallerani and Palazzo Segardi. He died in Florence in 1849.

His son Agostino Ademollo (1799–1841) was a writer of romances, including Marietta di' Ricci. His nephew Carlo Ademollo was a history and battle scene painter.