Gabriël Metsu was a Dutch painter of history paintings, still lifes, portraits, and genre works. He was "a highly eclectic artist, who did not adhere to a consistent style, technique, or one type of subject for long periods". Only 14 of his 133 works are dated.

Gabriel Metsu was the son of Jacques Metsu (c. 1588 – March 1629) a tapestry worker and painter originally from Hainault, who lived most of his days at Leiden, and Jacquemijntje Garniers (c. 1590 – 8 September 1651), the widow of a painter with three children of her own. It is not known when and where Gabriel was baptized; most likely in a Catholic hidden church but the baptismal records did not survive. Gabriel grew up on Lange Mare and his stepfather, a skipper, must have supported his education, because his mother was a poor midwife.

In 1648 Metsu was registered among the first members of the painters' guild at Leiden. In 1650 he ceased to subscribe. Metsu was possibly trained in Utrecht by the Catholic painters Nicolaus Knüpfer and Jan Weenix.

Around 1655 Metsu moved to Amsterdam; he lived in an alley on Prinsengracht, next to a brewery and near his relatives, the children of the sugar refiner Philips Metsu. In 1657 he got into an argument with a neighbor. (It was alleged that Metsu left a brothel at six in the morning.) Gabriel moved to a house on the canal side, where a daily vegetable market was held. In 1658 he married Isabella de Wolff, whose father was a potter and mother the painter Maria de Grebber.

At the onset of the 1660s Metsu turned for inspiration to the art of the "fijnschilders" from his native Leiden. Metsu was responding to the market of Dou's paintings, who sold his paintings all over for exorbitant prices. Metsu may have also influenced Pieter de Hooch.

For a while Metsu trained Michiel van Musscher and Joost van Geel. Metsu died at the age of 38 and was buried in the Nieuwe Kerk. Three bells were tolled; a habit in use with Dutch Catholics at that time. His widow left for Enkhuizen, to live with her mother. Isabella was buried in the Zuiderkerk in 1718.