Edward Dufner was an American painter and art teacher.

Dufner was born in 1872 in Buffalo, New York. He attended the Art Students League of New York, the Académie Julian, and the Académie Carmen.

Dufner taught at the Art Students League of Buffalo and New York, the Carnegie Institute of Technology, and the Traphagen School of Fashion. He became an Impressionist painter, and he won the Pennsylvania Academy of Fine Arts's Walter Lippincott Prize in 1924.

Dufner married Fern Bradley. He died on October 1, 1957, at age 86, and he was buried in Beaufort, South Carolina.