Giorgio di Giovanni, also known as Giorgio da Siena was an Italian painter of the Renaissance period, active mainly in Siena.

Little is known about the life of the painter. His work, for example the frescoes at the Castello di Belcaro, have been also been attributed to Baldassare Peruzzi. Other works such as the Flight of Cloelia have been attributed to Domenico Beccafumi and Marco Bigio. Giorgio di Giovanni is known to have worked circa 1525–1530 on the Vatican Loggie in Rome along with Giovanni da Udine.