George Clare lived and died in Barnet, Hertfordshire; although it is known that he spent some time (during the 1860's) in Birmingham evidenced by the fact that his address is given as 173, Bristol Street, Birmingham for the paintings he exhibited during the 1860's. As to George's artistic training, one is not sure; however, his technique is a delicate stippling as he was greatly influenced by William Hunt.

Two of George's sons, Oliver and Vincent, were also artists and became quite famous for their still life and flower paintings.