Francesco Bissolo was a Venetian painter of the Renaissance. He is also known as Pier Francesco Bissolo.

He is described as a pupil of Giovanni Bellini. He painted a Christ exchanging crown of thorns for crown of gold with St. Catherine for the church of il Redentore, now at the Gallerie dell'Accademia in Venice, and a Santa Giustina in Treviso cathedral. He painted a Holy Family with donor in landscape found at the Dayton Art Institute in Ohio, United States.

He died in the contrada of S. Marciliano on 20 April 1554 after six months of illness.