Pieter van Huffel was a Belgian artist.

After an initial apprenticeship with his uncle and godfather Pierre Canivé, paintings conservator in Geraardsbergen, Pieter Van Huffel integrated the Royal Academy of Fine Arts in Ghent. He continued his training in Antwerp, Mechelen and in Paris, where he copied the old masters, and worked for a time in David's studio.

During the French period of the Netherlands, he was director-artist and professor of the Academy of Ghent and curator of the Museum of Fine Arts in the city. His career continued under the United Kingdom of the Netherlands: Honorary painter Princess of Orange, a member of the Royal Institute, he was also a member of the regency of Ghent and deputy provincial States.

There are several known religious compositions by Van Huffel, but he was mainly a portraitist, immortalizing the faces of the politicians and notables of Ghent.