Francesco de Mura was an Italian painter of the late-Baroque period, active mainly in Naples and Turin. His late work reflects the style of neoclassicism.

Francesco de Mura, also referred to as Franceschiello, was a pupil of Francesco Solimena, then later with Domenico Viola, where he met his contemporary, Mattia Preti.

While still in his teens he painted frescoes (1715) in San Nicola alla Carità in Naples. He painted ten canvases of the Virtues and an Adoration of the Magi (1728) for the church of Santa Maria Donnaromita. His other works include frescoes of the Adoration of the Magi (1732) in the apsidal dome of the church of the Nunziatella. De Mura also painted portraits.

Among his pupils was Pietro Bardellino and Girolamo Starace.