Edward Antoon Portielje was a Belgian genre painter.

He was born to the painter, Jan Portielje, and his wife Eulalie née Lemaire (1828-1903). His older brother, Gerard, was also a genre painter.

His first art lessons came from his father. Next, he attended the Royal Atheneum and, from 1873, took after-school classes at the Royal Academy of Fine Arts, with Edward Dujardin. From 1877 to 1881, he was a full-time student there, under the tutelage of Polydore Beaufaux, Charles Verlat and Nicaise de Keyser.

He was married twice, first to Jeanne Marie Cochet then, in 1888, to Rosa Hermans, with whom he had a son. During World War I he lived in Brussels; returning to Antwerp in 1919.

Genre scenes were his speciality, with an occasional portrait or seascape. Much of his inspiration came from the fishing communities in Zeeland. Many of his works are series of similar interior scenes, created according to the wishes of his agents, Albert D'Huyvetter [nl] and Guillaume Campo (1880-1952). They generally consist of a room with a sunny window, occupied by women in traditional costume, engaged in some daily activity. These paintings were very popular; selling throughout Europe and the United States.

In 1894, he worked together with Edouard de Jans and Joseph Dierickx to create murals for the Exposition Internationale d'Anvers.