Francis Alexander was an American portrait-painter.

Alexander was born in Windham county Connecticut in February 1800. Brought up on a farm, he taught himself the use of colors, and in 1820 went to New York City and studied painting with Alexander Robertson.

He spent the winters of 1831 and 1832 in Rome. Afterwards, he resided for nearly a decade in Boston, Massachusetts, where he had considerable vogue, and where he painted a portrait of Charles Dickens (1842).

In 1840 he was elected to the National Academy of Design as an honorary member. There is a tradition that when Dickens visited Boston, a line of New England portraitists was already fawning on shore, hoping to be the first to capture the great novelist's image on canvas. But Francis Alexander reached the writer well ahead of his peers—by traveling in a small advance boat to greet Dickens as his vessel entered the harbor. American poet Henry Wadsworth Longfellow (whom Alexander also painted) would later coin the verb Alexandered (as in, wangled), sniffing that such and such a person had Alexandered his way into a highly coveted invitation to a party. Francis Alexander died in 1881 in Florence.