Isidore Verheyden was a Belgian painter of landscapes, portraits and still life.

He was the son of painter Jean-François Verheyden; his first teacher at the Académie Royale des Beaux-Arts of Brussels was Joseph Quinaux, and in 1866 he entered the studio of Jean-François Portaels for further study. He also studied under the landscape painter Théodore Baron; he in turn taught Anna Boch.

Verheyden was a founding member of the anti-academic Société Libre des Beaux-Arts in 1868, and a member of Les XX from 1884 to 1886.