Thomas Hosmer Shepherd was a British topographical watercolour artist well known for his architectural paintings.

Thomas was the brother of topographical artist George "Sidney" Shepherd, Thomas was employed to illustrate architecture in London, and later Edinburgh, Bath and Bristol. His paintings were the basis for steel engravings in many books (see bibliography).

Shepherd's work, mostly topographical, is characterized by an attention to detail, along with lifelike scenes that contained people, carriages and horses. His first acclaim came with Metropolitan improvements, a publication of modern London architecture commissioned by the publisher Jones & Co. He worked mostly for Frederick Crace, who employed him to paint old London buildings prior to their demolition, with much of the work surviving in the Crace collection at the British Museum.

Shepherd lived in Batchelor Street, Islington, North London. His residency is marked by a commemorative plaque.