Herbert William Weekes was a well-known English genre and animal painter of the Victorian Neoclassical period who specialized in portraying animals in humorous, human-like situations.

Weekes was born in Pimlico, London, England to a prominent artistic family: the youngest of five children, his father, Henry Weekes, Sr. (1807–1877), was a sculptor and Royal Academician; his brother, Henry, Jr. (fl. 1850–1884), was also a genre painter known for his animal studies; and his brother, Frederick (1833–1920), was an artist and expert on medieval costume and design.

Weekes appears to have used his middle name, William, for all but formal purposes. He lived and worked for most of his life in London, at 21 Oppidans Road, Primrose Hill. In 1865, he married artist Caroline Anne Henshaw (born ca. 1844), of Hammersmith.

Known as an animal and genre painter of the Victorian Neoclassical style, Weekes' work was popular, and helped expand 19th century animal painting from its traditional role of simply recording beasts into a way of reflecting human life. He frequently personified animals and placed them in situations particular to humans. His work shows a sensitive understanding of his subject matter, and part of his success in capturing the peaceful country atmosphere depicted in so many of his paintings lay in his affection for it. He was greatly influenced by one of the foremost animal painters of the nineteenth century, Sir Edwin Henry Landseer.

Weekes contributed illustrations for The Illustrated London News in 1883, and exhibited extensively in various London and provincial galleries. His works were well received - although not by everyone: a contemporary wit described his paintings as “Weekes' Weak Squeaks”.

Weekes died on 21 November 1914 and was buried on 28 November in Hampstead Cemetery (West Hampstead) - the grave is in Section C11 Grave 145, the service was performed by the Vicar of St Luke's Church Hampstead.